Akihiro Hoshino Selected Research

X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation

1/2022	A case of autoimmune enteropathy with CTLA4 haploinsufficiency.
11/2019	Hematopoietic stem cell transplantation recovers insulin deficiency in type 1 diabetes mellitus associated with IPEX syndrome.
1/2019	Identification of autoantibodies using human proteome microarrays in patients with IPEX syndrome.

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Akihiro Hoshino Research Topics

Disease

7	Esophageal Neoplasms (Esophageal Cancer) 12/2021 - 03/2014
4	Stomach Neoplasms (Stomach Cancer) 12/2022 - 07/2010
4	Esophageal Squamous Cell Carcinoma 05/2022 - 01/2018
4	Neoplasms (Cancer) 01/2021 - 11/2013
3	Adenocarcinoma 03/2022 - 10/2012
3	X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation 01/2022 - 01/2019
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 01/2017
3	2 X-Linked Lymphoproliferative Syndrome 01/2022 - 01/2017
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2022 - 01/2017
2	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2022 - 01/2014
2	Splenomegaly 01/2022 - 01/2017
2	Diarrhea 01/2022 - 01/2017
2	Cicatrix (Scar) 01/2021 - 09/2011
2	Infections 11/2020 - 09/2011
2	Paralysis (Palsy) 10/2019 - 01/2019
2	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 10/2018
2	Hemorrhage 01/2019 - 03/2015
2	Bruton type agammaglobulinemia 02/2016 - 02/2015
2	Disease Progression 02/2015 - 09/2011
1	Pathologic Constriction (Stenosis) 01/2022
1	Epstein-Barr Virus Infections 01/2022
1	Eosinophilia 01/2022
1	Atrophy 01/2022
1	Rare Diseases (Rare Disease) 01/2022
1	Autoimmune enteropathy 01/2022
1	Dysbiosis 10/2021
1	Esophageal Stenosis (Esophageal Stricture) 01/2021
1	Primary Immunodeficiency Diseases 01/2021
1	Job Syndrome (Hyper-IgE Syndrome) 01/2021
1	Ulcer 01/2021
1	Fusariosis 03/2020
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2019
1	Pancytopenia 01/2019
1	Muscle Hypotonia (Hypotonia) 01/2019
1	Afibrinogenemia (Fibrinogen Deficiency) 01/2019
1	Pneumothorax 01/2019
1	Inflammation (Inflammations) 11/2018
1	Squamous Cell Carcinoma of Head and Neck 08/2018
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2018
1	Wiskott-Aldrich Syndrome 01/2018
1	Down Syndrome (Down's Syndrome) 05/2017
1	Hematologic Neoplasms (Hematological Malignancy) 05/2017
1	Leukemia 05/2017
1	Stomatitis 01/2017
1	Hepatomegaly 03/2015
1	Neuroblastoma 03/2015
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 02/2015
1	Respiratory Insufficiency (Respiratory Failure) 08/2014
1	Vocal Cord Paralysis 03/2014
1	IGA Glomerulonephritis (IGA Nephropathy) 01/2014
1	Thrombocytopenia 1 01/2014

Drug/Important Bio-Agent (IBA)

3	X-Linked Inhibitor of Apoptosis ProteinIBA 01/2022 - 01/2017
2	AutoantibodiesIBA 01/2022 - 01/2019
2	Busulfan (Busulfex)FDA Link 01/2021 - 05/2017
2	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 01/2017
2	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 01/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 09/2011 - 05/2010
1	AntigensIBA 01/2022
1	LigandsIBA 01/2022
1	Interleukin-2 (IL2)IBA 01/2022
1	IodineIBA 12/2021
1	Triamcinolone (Aristocort)FDA Link 01/2021
1	SteroidsIBA 01/2021
1	Melphalan (Alkeran)FDA LinkGeneric 01/2021
1	fludarabineIBA 01/2021
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021
1	DNA Ligase ATPIBA 11/2020
1	VaccinesIBA 11/2020
1	Insulin (Novolin)FDA Link 11/2019
1	ProteomeIBA 01/2019
1	I-kappa B KinaseIBA 11/2018
1	Viral DNAIBA 10/2018
1	Lugol's solution (Lugol's iodine)IBA 08/2018
1	CarcinogensIBA 01/2018
1	Docetaxel (Taxotere)FDA Link 01/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2018
1	Clofarabine (Clolar)FDA Link 05/2017
1	Signaling Lymphocytic Activation Molecule Associated ProteinIBA 01/2017
1	Phosphopyruvate Hydratase (Enolase)IBA 03/2015
1	Anaplastic Lymphoma KinaseIBA 02/2015
1	Pre-B Cell ReceptorsIBA 02/2015
1	Immunoglobulins (Immunoglobulin)IBA 02/2015
1	Agammaglobulinaemia Tyrosine KinaseIBA 02/2015
1	RNA (Ribonucleic Acid)IBA 02/2015

Therapy/Procedure

8	Esophagectomy 01/2022 - 03/2014
6	Lymph Node Excision (Lymph Node Dissection) 12/2022 - 07/2010
6	Therapeutics 11/2019 - 05/2010
5	Gastrectomy 12/2022 - 07/2010
4	Hematopoietic Stem Cell Transplantation 03/2020 - 08/2014
3	Cell Transplantation 10/2021 - 05/2017
3	Drug Therapy (Chemotherapy) 01/2018 - 10/2012
1	Blood Transfusion (Blood Transfusions) 03/2022
1	Lasers (Laser) 12/2021
1	Length of Stay 01/2019
1	Thoracotomy 01/2019
1	Transplantation 05/2017
1	Stem Cell Transplantation 02/2016
1	Artificial Respiration (Mechanical Ventilation) 08/2014
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2014
1	Hepatectomy 11/2013